MTEC Solicitation Summary: Fiscal Year 2026 Multi-Topic Request for Project Proposals

Special Notice from the Defense Health Agency (dha), for work in Frederick, Maryland. Due Oct 30, 2026, 12:00 PM (UTC-4), 12 days left.

Official notice and attachments

Description

A summary of Amendment 01 to this Request for Project Proposals has been posted to SAM.gov on 09 October 2026. The only change incorporated within this summary announcement is the addition of Focus Area 16 ("Multisite Clinical Biomarker Platform for Trauma-Related Lung and Kidney Failure"). The full version of the amendment (as well as the original RPP) is available on MTEC's website (https://mtec-sc.org/) and includes additional changes/updates. The Medical Technology Enterprise Consortium (MTEC) is excited to post this summary announcement for a Request for Project Proposals (RPP) soliciting a broad range of medical prototype technological and knowledge solutions related to the Focus Areas of Interest (also called “Focus Area(s)”) listed below.

Proposed solutions may include medical techniques, knowledge products, and materiel (e.g., medical devices, drugs, and biologics). Military relevance is a key feature of this RPP. Awards resulting from this RPP are expected to be made under the authority of 10 U.S.C. § 4022 (Authority of the Department of Defense to carry out certain prototype projects).

As stated at the end of this announcement, the full RPP is posted to the MTEC website (https://mtec-sc.org/); this notice is intended only to notify interested parties of the available solicitation. ____________________________________________________________________________________ Background: Current wartime operations assume that the United States and our allies will maintain air, land, maritime, space and cyber superiority.

Future conflicts against peer and near-peer adversaries are expected to be layered stand-offs and fought across multiple domains. Mission success will be determined by our ability to compete to expand the competitive space, penetrate both strategically and operationally, disintegrate enemy’s defenses, exploit enemy weaknesses, and re-compete to consolidate gains. Medical capabilities play a critical role in each aspect of the future battlespace and must modernize rapidly to maintain Force readiness and increase soldier lethality.

Focus Areas: To meet the intent of the RPP, each Enhanced White Paper proposal SHALL specifically address ONLY ONE Focus Area described below. Offerors are not limited to a single Enhanced White Paper proposal submission. Projects that fail to align with only one of these Focus Areas may not be considered for funding.

The following Focus Areas of Interest are not listed in order of importance; the detailed requirements for each are described in the full version of the Request for Project Proposals. Focus Area 1: Policies and practices for cross-cutting prevention – the aim of this focus area is to develop and evaluate non-training interventions/activities that address risk and protective factors for harmful behaviors.

Priority risk/protective factors to address include: morale, fairness, work-life balance, passive leadership, toxic leadership, and workplace hostility. Focus Area 2: Fostering Service member physical fitness through integrated primary prevention – the aim of this focus area is to develop interventions or trainings to combat the key contributors to force readiness and physical fitness.

This focus area encourages offerors to consider resource/environmental constraints and social and psychological barriers present for warfighters when developing solutions. Focus Area 3: Identify and reduce barriers to help-seeking – the aim of this focus area is to identify and develop prototypes against key drivers of help-seeking. Proposed prototypes should prioritize high-impact resources/services and Service member populations at elevated risk for harmful behaviors.

Focus Area 4: Prophylactic Solutions to Prevent Battlefield and Complex Traumatic Wound Infections in Austere or Contested Environments – the aim of this focus area is the development of prototypes to prevent or delay wound infections (bacterial, fungal, and/or antimicrobial-resistant) following battlefield and complex traumatic wounds, including in austere or contested environments, for use at the point of injury and in prolonged care environments (Roles 1 and 2), without negatively impacting wound healing.

High-priority pathogens include Pseudomonas aeruginosa, Klebsiella pneumoniae, Acinetobacter baumannii, Staphylococcus aureus, and invasive fungal infections. NOTE: This focus area is not interested in vaccines, burn wound solutions, or discovery-stage efforts. Focus Area 5: Pathogen Agnostic Countermeasures for the Treatment of Sepsis Caused by Wound Infection – the aim of this focus area is the development of products, including immune modulators, novel drugs, immunotherapeutics, and other pathogen-agnostic and/or host-directed prototypes, to treat sepsis following battlefield and complex traumatic wounds (excluding burn wounds), including in austere or contested environments.

NOTE: This focus area is not interested in vaccines, burn wound solutions, discovery-stage efforts, or proposals focused solely on direct treatment of wound infection rather than sepsis. Focus Area 6: Knowledge Product Prototypes for the Prevention of Infection in Traumatic Penetrating Wounds – the aim of this focus area is the development of knowledge product prototypes to optimize clinical practice guidelines for the prevention of infection in traumatic penetrating wounds.

Focus Area 7: Bacterial Diarrhea Prevention – the aim of this focus area is the development of prototypes to prevent bacterial diarrhea resulting from high-priority pathogens (Campylobacter jejuni, enterotoxigenic Escherichia coli, and Shigella) in operational settings. NOTE: Proposals targeting other pathogens will be deemed out of scope. Furthermore, this focus area will not consider proposals for vaccine-based interventions.

Focus Area 8: Dengue Fever Prevention and/or Treatment Solutions – the aim of this focus area is the development of drugs and vaccines to prevent or treat all four serotypes of Dengue Fever. N

The description continues in the official notice.

Similar open research and development in the physical, engineering, and life sciences (except nanotechnology and biotechnology) bids