GREGoRi Innovation Projects (U01 Clinical Trial Optional)
Updated
Cooperative agreement from the National Institutes of Health, open to small businesses. Closes Oct 30, 2026, 10 days left.
| Opportunity number | RFA-HG-27-013 |
|---|---|
| Agency | National Institutes of Health |
| Funding type | Cooperative agreement |
| Field | Health |
| Award ceiling | $500,000 |
| Award floor | $3 |
| Expected number of awards | 10 |
| Total program funding | $7.5 million |
| Cost sharing or matching | Not required |
| Assistance listing | 93.172 |
| Posted | Jun 18, 2026 |
| Closes | Oct 30, 2026 (10 days left) |
| Add the deadline to | Google Calendar |
Who can apply
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and state controlled institutions of higher education
- Native American tribal governments (federally recognized)
- Public housing authorities and Indian housing authorities
- Native American tribal organizations (other than federally recognized tribal governments)
- Nonprofits with 501(c)(3) status, other than institutions of higher education
- Nonprofits without 501(c)(3) status, other than institutions of higher education
- Private institutions of higher education
- For-profit organizations other than small businesses
- Small businesses
- Others (see the eligibility notes)
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Description
The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. This Notice of Funding Opportunity is intended to stimulate the development and testing of highly innovative experimental or computational approaches for rare disease diagnosis, that have the potential to make transformative improvements to the current state of the art.
Full announcement and how to apply on Grants.gov
Health grants right now
There are 350 open federal grants in health that small businesses may apply for; 33 close within 30 days. The median award ceiling is $500,000; this grant offers up to $500,000. The agencies offering the most are National Institutes of Health, Centers for Disease Control and Prevention - ERA and Centers for Disease Control - NCBDDD. Grants in this field stay open a median of 1031 days; this one is open for 134 days.
Who has won this program before
- Mayo Clinic $78.4 million · from Sep 18, 2017
- Georgetown University $53.2 million · from Sep 18, 2014
- Baylor College Of Medicine $47.8 million · from Sep 28, 2011
- California Institute Of Technology $42.0 million · from Sep 18, 2019
- The Broad Institute, Inc $40.5 million · from Sep 19, 2018
The largest grants and cooperative agreements under assistance listing 93.172 with payments since Oct 1, 2025, from USAspending.gov. Amounts are each award's total.
Other open grants in the same program
Under assistance listing 93.172, the federal program this grant is paid from.
More open grants from the National Institutes of Health
340 open grants from this agency accept small businesses, with $356.4 million in total program funding listed.