Cellular Senescence Network (SenNet): Discovery, Validation Centers (UM1 Clinical Trials Not Allowed)
Updated
Cooperative agreement from the National Institutes of Health, open to small businesses. Closes Nov 23, 2026, 34 days left.
| Opportunity number | RFA-RM-27-016 |
|---|---|
| Agency | National Institutes of Health |
| Funding type | Cooperative agreement |
| Field | Health |
| Expected number of awards | 25 |
| Cost sharing or matching | Not required |
| Assistance listing | 93.310 |
| Posted | Oct 9, 2026 |
| Closes | Nov 23, 2026 (34 days left) |
| Add the deadline to | Google Calendar |
Who can apply
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and state controlled institutions of higher education
- Native American tribal governments (federally recognized)
- Public housing authorities and Indian housing authorities
- Native American tribal organizations (other than federally recognized tribal governments)
- Nonprofits with 501(c)(3) status, other than institutions of higher education
- Nonprofits without 501(c)(3) status, other than institutions of higher education
- Private institutions of higher education
- For-profit organizations other than small businesses
- Small businesses
- Others (see the eligibility notes)
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
Description
The purpose of this Notice of Funding Opportunity (NOFO) is to support SenNet Discovery and Validation Centers (SenNet DVCs) as a core component of Stage 2 of the NIH Common Fund Cellular Senescence Network (SenNet). Building on Stage 1 resources, DVCs will define, refine, and validate tissue- and disease-relevant cellular senescence signatures (“senotypes”) and associated biomarkers, and will investigate their functional consequences in human health and disease.
DVCs are expected to generate and contribute high-quality molecular, cellular, and spatial datasets (including relevant metadata and documentation) and to use complementary experimental systems, as appropriate, to validate senotypes/biomarkers and characterize responses to senescence-associated perturbations or senotherapeutic approaches. DVC applications should also propose goals and aims for SenNet consortium-wide organizational and outreach activities (SenNet OOC functions).
Full announcement and how to apply on Grants.gov
Health grants right now
There are 350 open federal grants in health that small businesses may apply for; 33 close within 30 days. The median award ceiling is $500,000. The agencies offering the most are National Institutes of Health, Centers for Disease Control and Prevention - ERA and Centers for Disease Control - NCBDDD. Grants in this field stay open a median of 1031 days; this one is open for 45 days.
Who has won this program before
- University Of North Carolina AT Chapel Hill $977.0 million · from Jun 29, 2006
- Fred Hutchinson Cancer Center $383.5 million · from Jun 29, 2006
- Icahn School Of Medicine AT Mount Sinai $250.0 million · from Mar 1, 2006
- Dana-Farber Cancer Institute, Inc. $235.8 million · from Dec 1, 1977
- Oregon Health & Science University $203.0 million · from May 1, 1997
The largest grants and cooperative agreements under assistance listing 93.310 with payments since Oct 1, 2025, from USAspending.gov. Amounts are each award's total.
Other open grants in the same program
Under assistance listing 93.310, the federal program this grant is paid from.
More open grants from the National Institutes of Health
340 open grants from this agency accept small businesses, with $356.4 million in total program funding listed.