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Notice of Intent - Illumina MiSeq i100 series instruments

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Presolicitation from the National Institutes of Health, for work in Bethesda, Maryland. Due Nov 27, 2026, 12:00 PM (UTC-5), 14 days left.

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Solicitation numberNOI-OLAO-CC-27-000836
AgencyNational Institutes of Health
OfficeNational Institutes of Health - Cc
Notice typePresolicitation
Set-asideNone
Trade (NAICS)Analytical Laboratory Instrument Manufacturing (334516)
Product or service code6640
Place of performanceBethesda, Maryland
PostedNov 12, 2026
Response deadlineNov 27, 2026, 12:00 PM (UTC-5) (14 days left)
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Bid documents (3)

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Federal prevailing wage rates for this place: Maryland Davis-Bacon and SCA wage determinations.

Description

This is a Notice of Intent, not a request for proposal. The National Institute of Health, Clinical Center (NIH-CC) intends to negotiate on an other than full and open competition basis with the following vendor: Illumina, Inc. Acquisition Description: The purpose of this acquisition is to purchase two Illumina MiSeq i100 series instruments. These instruments will be used by the NIH HLA Laboratory to produce high resolution HLA typing results for the numerous transplant protocols supported by the laboratory.

It will replace the current Illumina MiSeq instruments in the lab that were purchased in 2021 and 2022. The vendor will discontinue service on the current model of the MiSeq. New instruments are required to ensure time to validate these replacements before discontinuation of service.

The total dollar value for this order is $139,100.52. The MiSeq is an integrated instrument that performs clonal amplification, genomic DNA sequencing, and data analysis with base calling, alignment, variant calling, and reporting in a single run. The MiSeq provides the Lab with the highest HLA typing results possible.

The transplant protocols served by the HLA Lab require highest resolution possible to increase the chance of a successful transplant. The HLA Lab currently owns two MiSeq instruments, so the procedures and Quality Control assessments are in place. The order aims to replace the Illumina Miseq – s/n M07700 (property ID is 02223449) and s/n M08636 (property ID is 02268689) that were purchased in 2019 and 2022.

Replacement is necessary to ensure proper performance of these instruments prior to discontinuation of service for the current model of the Illumina MiSeq instruments by the vendor. The statutory authority for this sole source requirement is 41 U.S.C. 253(c) (1) as implemented by FAR 6.302-1 only one responsible source and no other supply of service will satisfy agency requirements.

This is not a request for proposal. All responsible sources that could provide the required may submit a capability statement that will be considered by email (subject line to reference NOI-OLAO-CC-27-000836) by 12:00 PM eastern standard time on 11/27/2026 to: [email protected]. All responses received by the closing date of this synopsis will be considered by the Government.

A determination not to compete this requirement, based upon responses to this notice, is solely within the discretion of the Government.

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Is your business small enough?

For NAICS 334516, a business counts as small if it has no more than 1,000 employees (SBA size standard). This notice is set aside, so only businesses under that size, or in the named program, can bid. SBA table, current as of Oct 15, 2026.

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About the buyer

The National Institutes of Health awarded $5.9 billion in contracts in the last 12 months; its biggest suppliers were Leidos Biomedical Research Inc, M. A. Mortenson Company and Deloitte Consulting LLP. See what NIH is buying now.

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There are 90 open government contract opportunities in this trade (NAICS 334516), 39 posted in the last 7 days; 52% are set aside for small businesses. The agencies buying the most are Department of Veterans Affairs, Department of Energy and National Institutes of Health. Most of the work with a stated place is in Maryland, New Mexico and Ohio. A notice in this trade gives a median of 14 days from posting to deadline; this one gives 15 days.

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