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Simulation-augmented, Real-time Platform Adaptive Seamless Trials (SURPASS)

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Solicitation from the National Institutes of Health. Due Nov 30, 2026, 5:00 PM (UTC-5), 16 days left.

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Solicitation numberARPA-H-SOL-26-164
AgencyNational Institutes of Health
OfficeAdvanced Research Projects Agency for Health (ARPA-H)
Notice typeSolicitation
Set-asideNone
Trade (NAICS)Research and Development in Biotechnology (except Nanobiotechnology) (541714)
Product or service codeAN13
PostedNov 13, 2026
Response deadlineNov 30, 2026, 5:00 PM (UTC-5) (16 days left)
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Description

13 NOV: Amendment 1 provides minor revisions to the ISO (see orange text). The link to the SURPASS webinar has also been added to this posting. 30 SEP: The Advanced Research Projects Agency for Health (ARPA-H) posts this solicitation in support of its Simulation-augmented, Real-time Platform Adaptive Seamless Trials (SURPASS) Program.

ARPA-H anticipates multiple Other Transaction Agreement awards will result from this opportunity. Interested parties are invited to review the attached Solicitation (ARPA-H-SOL-26-164) and associated attachments. As detailed in Special Notice ARPA-H-SN-26-164, ARPA-H will host an informational webinar on 15 OCT 2026 and a 2-day Proposers’ Day on 6 and 9 NOV 2026 in support of SURPASS.

All questions related to SURPASS should be submitted to [email protected].

Contracting contact

As published on the official notice. Ask questions in writing and before any questions deadline the notice sets.

Is your business small enough?

For NAICS 541714, a business counts as small if it has no more than 1,000 employees (SBA size standard, with exceptions in the notes). This notice is not set aside, but the size decides your small business status on it. SBA table, current as of Oct 15, 2026.

Notice history

Companies that win this kind of work

Federal contractors paid for research and development in biotechnology work, who also hold NIH contracts (last 12 months): possible competitors, or partners to team with.

About the buyer

The National Institutes of Health awarded $5.9 billion in contracts in the last 12 months; its biggest suppliers were Leidos Biomedical Research Inc, M. A. Mortenson Company and Deloitte Consulting LLP. See what NIH is buying now.

Research and Development in Biotechnology contracts right now

There are 34 open government contract opportunities in this trade (NAICS 541714), 5 posted in the last 7 days; 50% are set aside for small businesses. The agencies buying the most are National Institutes of Health, Defense Advanced Research Projects Agency (DARPA) and Defense Health Agency (DHA). Most of the work with a stated place is in Maryland, New Mexico and District of Columbia. A notice in this trade gives a median of 49 days from posting to deadline; this one gives 17 days.

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