Amendment 1

ARPA-H-SOL-26-162, UNIQUE

INNOVATIVE SOLUTIONS OPENING

FOR

UNIFYING IMAGING WITH QUANTUM ENTANGLEMENT

UNIQUE

HEALTH SCIENCE FUTURES

ARPA-H-SOL-26-162

SEPTEMBER 16, 2026

ARPA-H-SOL-26-162, UNIQUE

not defined.
3.1.1

PROHIBITION OF PERFORMER PARTICIPATION FROM FEDERALLY FUNDED

RESEARCH AND DEVELOPMENT CENTERS (FFRDCs) AND OTHER GOVERNMENT

3.1.2

3.1.3

3.2

4.1

4.2

4.3

4.4

4.5

5.1

5.2

5.3

5.4

5.4.1

5.4.2

CRITERIA 2: PROPOSER’S CAPABILITIES AND/OR RELATED EXPERIENCE

5.4.3

CRITERIA 3: POTENTIAL CONTRIBUTION TO RELEVANCE TO THE ARPA-H

5.4.4
5.5

ARPA-H-SOL-26-162, UNIQUE

5.6

6.1 CONTROLLED UNCLASSIFIED INFORMATION (CUI) ON NON-FEDERAL

6.3

6.4

6.5

6.6

PROCUREMENT OF SYNTHETIC NUCLEIC ACIDS OR BENCHTOP

6.7

APPENDIX A: Solution Summary Content and Instructions
APPENDIX B: Full Proposal Content and Instructions

ARPA-H-SOL-26-162, UNIQUE

INNOVATIVE SOLUTIONS OPENING (ISO) SUMMARY INFORMATION

FEDERAL AGENCY: Advanced Research Projects Agency for Health (ARPA-H) PROGRAM TITLE: UNifying Imaging with QUantum Entanglement (UNIQUE) ANNOUNCEMENT TYPE: Innovative Solutions Opening (ISO)

ISO SOLICITATION NUMBER: ARPA-H-SOL-26-162

ISO CONTACT: [email protected]

ANTICIPATED AWARDS: Other Transactions
DATES: (All times listed are Eastern Time)
Posting Date: September 16th, 2026
In Person and Virtual Only Proposers’ Day (PD): October 16th, 2026, 8:30 AM Proposers’ Day Video Link: https://arpa-h.gov/explore-funding/programs/unique Lightning Talk / Sidebar session: October 16th, 2026, 3:00 - 5:00 PM Solution Summaries Due: October 29th, 2026, 5:00 PM
Full Proposals Due: December 15th, 2026, 5:00 PM

WHERE TO SUBMIT:

Solution Summaries: https://solutions.arpa-h.gov/Submit-Solution/ Proposals: https://solutions.arpa-h.gov/Submit-Proposal/ Questions: https://solutions.arpa-h.gov/Ask-A-Question/

PROPOSERS’ DAY

ARPA-H will host a Proposers’ Day in support of the UNIQUE program as described in Special Notice ARPA-H-SN-26-126. The purpose is to provide potential proposers with information on the UNIQUE program, promote additional discussions, and encourage teaming and networking.
Interested proposers are not required to attend, and materials formally presented during Proposers’ Day will be posted to the ARPA-H Program Webpage (https://arpa-h.gov/explorefunding/programs/unique) and on SAM.gov. ARPA-H will not reimburse potential proposers for participation at Proposers’ Day (or time and effort related to developing submissions in response to this ISO).

ARPA-H-SOL-26-162, UNIQUE

1. INTRODUCTION TO UNIQUE

1.1 BACKGROUND

Every major revolution in medical imaging has been driven by a new way to measure biology.