Draft Statement of Work

NCI 2026 Cervical Cancer Screening Follow- up
Statement Of Work
Independently and not as an agent of the Government, the Contractor shall furnish all the necessary services, qualified personnel, materials, equipment, and facilities, not otherwise provided by the Government as needed to perform the work as defined below. A.

BACKGROUND

Despite Human Papillomavirus (HPV) vaccines, screening will remain central for decades to control cervical cancer. Recently, HPV testing alone or with cytology was introduced in the US as an alternative to cytology screening. However, most HPV infections are harmless, and additional tests are required to identify women at highest cancer risk.
The National Cancer Institute (NCI) has analyzed data for over 1.5 million women screened for cervical cancer at Kaiser Permanente Northern California (KPNC) clinics. In addition, National Cancer Institute (NCI) has funded previous studies conducted at Kaiser Permanente Northern California to collect biospecimens for biomarker testing and to study risk estimates for cervical cancer screening. To continue these efforts and generate long-term risk estimates, follow-up, de-identified clinical data from participants in these studies is required.
B.

PURPOSE AND OBJECTIVES OF THE PROCUREMENT

The NCI will follow the status of women undergoing cervical cancer screening at KPNC. This follow-up requires the Contractor to provide detailed clinical and risk factor history and follow-up data for women enrolled in previous studies. The Contractor shall provide the deidentified results of all HPV and cytology-based testing as well as all colposcopy, biopsy and treatment procedures, as well as relevant co-factor data, within their screening program for women as follows: 1. The Contractor shall use existing laboratory and clinical datasets within the integrated health services delivery system to deliver the following data to NCI: age at visits, STD information (chlamydia, HIV, gonorrhea), hormonal contraception use, smoking status, BMI, and entire history of HPV, Pap results, and all coded cervical, endometrial and ovarian histology results (from biopsy, excisional procedures or hysterectomy), HPV vaccination, previous and future enrollment status. Cervix histology results not previously coded shall be coded prior to delivery of the dataset. 2. The data shall be provided as data sets and are based on evaluations and analysis made over the course of a year. The contractor shall provide a data set every year. The total number of data sets