IHS Combined Synopsis Solicitation Gene

012ÿ456789 ÿ2 95 8ÿÿ2588859ÿ 9 5



  ÿ!"ÿ1 # 1ÿ ÿ1$ ÿ2 %042ÿ&ÿ0 0 ÿ1 # 1
2 %04
'()*+,*ÿ.*/)0*ÿ120(+3ÿ'2*+24ÿ5ÿ67ÿ8ÿ779:ÿ;/<ÿ'()*+,*<ÿ=>ÿ96?

@ABCDEFGÿIJEAKIDIÿLÿIAMD@DNONDAE

',PP24Q)0(ÿR4,/SQ+TÿUÿ;V=ÿVW;ÿX04+ÿ7ÿY;2Z,(S+),*04[ÿVW;ÿ=Z2430S(\

09 89ÿ26ÿ]^89 ÿ59568ÿ98ÿ_02]`ÿ2 a 8

0^89bÿ5cc8
2588859ÿ 5d
8
0^ ÿ
042ÿÿ8lÿ9 
5 ^2 q8ÿ45

2 a8 ÿ^s58

988 ÿ59ÿ
_`ÿ5cÿ c569
 85 ÿÿ 8q 
x^5ÿ^
2^768ÿ5

~dÿ0 !$4 0!

'()*+,*ÿ.*/)0*ÿ120(+3ÿ'2*+24
7:?e79efe
g.8h8ÿih;j.'hi

8,Z2Pk24ÿ5,MB

:<ÿ77?
m7667ÿ5ÿ.*/ST+4)0(ÿg0S*/2424TÿYT)n2ÿT+0*/04/ÿo:9pÿP)((),*\ m6r
.*/)0*ÿiP0((ÿtST)*2TTÿhQ,*,P)Qÿh*+24R4)T2ÿY.ithh\ÿi2+eWT)/2ÿY;V=ÿ11iW; 67?p?6eYQ\uÿ67?p?:e7\

V)4PeV)v2/eX4)Q2ÿYVVX\

'()*+,*ÿ.*/)0*ÿ120(+3ÿ'2*+24<ÿ67ÿ8ÿ779:ÿ;/<ÿ'()*+,*<ÿ=>ÿ96? 7ww77?ÿeÿw6w779<ÿt0T2ÿX(STÿ7ÿ=R+),*ÿX24),/T
12,MB
8,Z2Pk24ÿ<ÿ77?ÿ0+ÿ7yÿXzÿ'{
P)T+)pkSTT2((|)3Tp},Z

€‚ÿ‚ÿ„ÿ†‡ˆ‰Š‹ÿ‚Œ‰†‚‚Ž‚†„†‰ÿ‘†’ÿ†‡‡Š’„ÿ’†‹“‚ÿ’Š„’Š‹ÿ‰ÿ„ †’‹„‰Šÿ”€ÿ•–— –˜•ÿ„’ÿ™š›ÿ“‚‰œÿ€Šÿ†‡ˆ‰Š‹ÿ‚Œ‰†‚‚Ž‚†„†‰ÿ‘†’‡„ÿ„ÿ•–—ÿ–˜•ÿ™ššžšŸˆ›ÿ¡¢ÿ£¤¥¦¢¤§ ¨©§¤£ÿª«¤ÿ¬¤¥­®¨ª¦­©¡£¯ÿ°O¬ÿA¥¤£«¡¨®ÿ„‰‹ÿ€Šÿ‡Š‡Š‰‰œÿ±±²Ž³±²ÿ„‚‚ÿ‹Š´„†‰›ÿ„‰‹ÿ€Š ‚‡‘Š‹ÿ’†Š‹“’Š‚ÿ‘†’ÿ†‡‡Š’„ÿ’†‹“‚ÿ„‰‹ÿ†‡‡Š’„ÿ‚Š’´Š‚ÿ„ÿ•–—ÿ–˜•ÿ™ššž™µ™ÿN«¦¢ ¡©©­¨©¶¤·¤©ªÿ¶­©¢ª¦ª¨ª¤¢ÿª«¤ÿ­©®¯ÿ¢­®¦¶¦ª¡ª¦­©¸ÿ¹¨­ª¡ª¦­©¢ÿ¡£¤ÿ£¤¹¨¤¢ª¤§ÿ¡©§ÿ¡ÿ¢¤º¡£¡ª¤ »£¦ªª¤©ÿ¢­®¦¶¦ª¡ª¦­©ÿ»¦®®ÿ©­ªÿ¼¤ÿ¦¢¢¨¤§½ÿ²†„†‰ÿ‰“‡ˆŠ’ÿš¾¿µšÀµÁµžžž™ÿ‚ÿ‚‚“Š‹ÿ„‚ÿ„ÿ•ŠÂ“Š‚ ‘†’ÿÁ“†„†‰ÿŸ•–Á ÿ‘†’ÿóÄÅÄÿ²Å•Æ³ÇŲÿ€‚ÿ„“‚†‰ÿ‚ÿ†‰‹“Š‹ÿ“‰‹Š’ÿ€ŠÿȓŒÿ³‰‹„‰ÿ˜ ÿŸšÉ ʝ²Çÿ¾Àÿ„‰‹ÿ±±²˜•ÿ²“ˆ„’ÿ˚¿¿ÿ€Šÿ„‚‚†„Š‹ÿĘ³Ç²ÿ†‹Šÿ‚ÿ̙šË˚ÿÍÿ³‰‹“‚’„ÿē‰‹Š’Š’‚ Ÿ‚ÎŠÿ‚„‰‹„’‹ÿϾÀžÿ‡†‰
•–—ÿ‰†ŠÐÿ•–—ÿ–˜•ÿɚš™šµËÿ„‰‹ÿɚš™šµÉÿ„’Šÿ’Š‡†´Š‹ÿ•Š’Š‚Š‰„†‰‚ÿ„‰‹ÿŠ’‘„†‰‚ÿ„’Š †ˆ„‰Š‹ÿ€’†“œ€ÿ€Šÿ†‘‘Š’†’Ñ‚ÿ„´Šÿ²˜Òœ†´ÿ’Šœ‚’„†‰Óÿ’ŠÂ“’Š‹ÿ„“‚Š‚ÿ„’Šÿ‹’„”‰ÿ‘’†‡ÿ€Šÿ•–— –˜•ÿ™ššžÉÿ„“‚Šÿ„ˆŠ‚

01234356278ÿ4 12642ÿ257ÿÿÿ  ÿ  ÿÿÿ !"ÿ#$ # ÿ %   ÿ %"!ÿÿ ÿ& ÿ '  ( ")ÿ*  ÿ ÿ+,-ÿ,.+ÿ/0)/12345ÿ$ # ÿ! ÿÿ%  ÿÿÿ$%ÿ$ÿ &"ÿÿ"ÿ  % ÿ "ÿ  5ÿ ÿÿ #&% ÿÿ' ÿ ""ÿ&ÿ%  ÿ3+,-ÿ,.+ÿ/0)/123 44)

67ÿ9:;<=9>?:ÿ?:;:@A>B=;>CB