Presol Notice SHS Coordinating Center 2

Pre-Solicitation Notice
Type: Pre-Solicitation
Notice Number: 75N92026R00010
Title: Strong Heart Study (SHS) – Coordinating Center
Classification Code: A – Research & Development
NAICS Code: 541715, Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology).
Posted Date: October 15, 2026
Response Date: October 30, 2026
Primary Point of Contact: Jonathan Lear, Contracting Officer, [email protected] Contracting Office Address
Department of Health and Human Services, National Institutes of Health, Office of Acquisition and Logistics Management (OALM), Research and Development and Professional Services – Division B, 6701 Rockledge Drive, RKL2, Bethesda, MD 20817 UNITED STATES. Introduction
The National Heart, Lung, and Blood Institute (NHLBI) is seeking a Coordinating Center to serve as part of the renewal of the program titled “Strong Heart Study”. This acquisition will designate a coordinating center to oversee new data collection from the existing cohort of participants and baseline data from newly recruited participants and maximize previously collected data and samples to address new questions about the development and progression of clinical cardiovascular disease and related conditions across the lifespan. The purpose of this announcement is to provide a Pre-solicitation Notice for the release of Solicitation No.

75N92026R00010. THIS NOTICE ADDRESSES THE COORDINATING CENTER ONLY. THIS IS A

SYNOPSIS. THIS IS NOT A SOLICITATION.
Background
The Strong Heart Study (SHS) is a long-running longitudinal observational study of two (2) combined cohorts followed prospectively: the original SHS cohort recruited in 1989 to 1991, and a Strong Heart Family Study (SHFS) cohort recruited in 1998 to 1999. The original and family cohorts together form the largest, multicenter, prospective epidemiological study of cardiovascular disease (CVD) in American Indians (AIs). The study’s main objective is to examine the etiology and natural history of cardiovascular disease in AIs.
Overall, there have been seven (7) phases of the study, with each phase corresponding to a multiyear project period. The current phase (Phase VII) is funded for the period from 2019 to 2027 and is comprised of a clinical exam, in addition to infrastructure support, morbidity and mortality surveillance, data analysis, and dissemination activities. More information about the SHS can be found on the SHS website: https://strongheartstudy.org/.