Statement of Work Bayesian Software 02

Statement of Work (SOW)
Electronic Drug Reference Subscription
Introduction and Overview

This statement of work is for a subscription to a Bayesian-guided medication dosing software from a contractor that can provide licensing rights. This subscription is to ensure clinicians have access to a reliable web-based therapeutic drug dosing and monitoring tool for complex clinical situations that require careful drug therapy evaluation and adjustment in a systematic and efficient manner. The software will include important pharmacokinetic parameters and empiric and patient-specific dosing recommendations; allow for graphical prediction and projection of theoretical doses at any drug dosing interval in order to optimize and achieve therapeutic drug levels; provide local storage of data and references for primary literature of clinicals models used; and lastly, be highly customizable, HIPAA and GDPR compliant, and meet VA information security requirements by only providing patient de-identification information on the web-based platform. Must be fully compliant with the IDSA/ASHP Vancomycin 2020 guidelines.

Background

Intravenous vancomycin remains an important first-line antibiotic used for treatment of serious methicillin-resistant Staphylococcus aureus (MRSA) infections. Recent Consensus Guidelines (Rybak MJ et al, AM J HEALTH-SYST PHARM, March 2020) for vancomycin therapeutic monitoring now recommend vancomycin dose optimization preferably using a Bayesian-guided software to achieve individualized targeted concentrations that maximize clinical efficacy while minimizing renal toxicity. Veterans Affairs Healthcare Systems are complex in scope of services; thus, clinical providers require access to a validated, systematic, and intuitive clinical tool to dose and monitor drug therapy safely.

Scope of Work

The contractor shall provide all resources necessary and have an established Business Associate Agreement with the Department of Veterans Affairs to meet requirements and accomplish the deliverables described in this statement of work (SOW), except as may otherwise be specified. The contractor shall provide uninterrupted licensing and subscription services to a Bayesian-guided medication dosing software as stated herein for clinical staff within the VA Salt Lake City Health Care System.

Performance Period
Contract will start December 12/1/2026 to 11/30/2027 with four 12-month renewal options. Period(s) of Performance:
12/1/2026 to 11/30/2027 Base Year
12/1/2027 to 11/30/2028 Option Year 1