Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)

Updated Oct 20, 2026

Grant from the National Institutes of Health, open to small businesses. Closes Nov 30, 2028, 772 days left.

Who can apply

• State governments
• County governments
• City or township governments
• Special district governments
• Independent school districts
• Public and state controlled institutions of higher education
• Native American tribal governments (federally recognized)
• Public housing authorities and Indian housing authorities
• Native American tribal organizations (other than federally recognized tribal governments)
• Nonprofits with 501(c)(3) status, other than institutions of higher education
• Nonprofits without 501(c)(3) status, other than institutions of higher education
• Private institutions of higher education
• For-profit organizations other than small businesses
• Small businesses
• Others (see the eligibility notes)

Other Eligible Applicants: Indian/Native American Tribal Governments (Other than Federally Recognized); Eligible Agencies of the Federal Government; U.S. Territory or Possession; Faith-based or Community-based Organizations; Regional Organizations; Non-domestic (non-U.S.) Entities (Foreign Organizations). Reminder: This NOFO supports administrative supplements to existing projects. To be eligible, the parent award must be active (i.e., not in a co-cost extension), and the research proposed in the supplement must be accomplished within the competitive segment. The proposed supplement must be to provide for an increase in costs due to unforeseen circumstances. All additional costs must be within the scope of the peer reviewed and approved project. IMPORTANT: The research proposed in the supplement application must be within the peer-reviewed scope of the NIH-supported grant project. Foreign Organizations/International Collaborations: All activities with foreign institutions must align with existing parent award. NIH will no longer issue awards (new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. This new requirement was effective, May 1, 2025. Applications involving foreign subawards/subcontracts submitted in response to this NOFO wil

Description

Current recipients of specific types of NIH research grants may apply for administrative supplements, using this Notice of Funding Opportunity (NOFO), to provide additional funding to a currently funded grant to meet increased costs that are within the scope of the peer-reviewed and approved project, but that were unforeseen when the new or competing renewal application was awarded.

Applications for administrative supplements are considered prior approval requests (as described in Section 8.1.2.11 of the NIH Grants Policy Statement) and will be routed directly to the Grants Management Officer of the parent award. There is no guarantee that funds are available from the awarding IC or for any specific grant. Therefore, prior to submission, applicants must discuss potential requests with the awarding ICO grants and program officials.

Full announcement and how to apply on Grants.gov

Health grants right now

There are 350 open federal grants in health that small businesses may apply for; 33 close within 30 days. The median award ceiling is $500,000. The agencies offering the most are National Institutes of Health, Centers for Disease Control and Prevention - ERA and Centers for Disease Control - NCBDDD. Grants in this field stay open a median of 1031 days; this one is open for 1100 days.

Who has won this program before

• Duke University $200.6 million · from Sep 21, 2016
• University Of North Carolina AT Chapel Hill $49.7 million · from Jul 1, 2007
• The General Hospital Corporation $49.2 million · from Jul 1, 2012
• Baylor College Of Medicine $47.8 million · from Sep 28, 2011
• Jackson Laboratory $47.2 million · from Sep 16, 2011

The largest grants and cooperative agreements under assistance listing 93.113, 93.121, 93.142, 93.143, 93.172, 93.173, 93.213, 93.233, 93.242, 93.273, 93.279, 93.286, 93.307, 93.310, 93.313, 93.350, 93.351, 93.361, 93.372, 93.393, 93.394, 93.395, 93.396, 93.399, 93.837, 93.838, 93.839, 93.840, 93.846, 93.847, 93.853, 93.855, 93.859, 93.865, 93.866, 93.867, 93.879, 93.989, 93.ECH with payments since Oct 1, 2025, from USAspending.gov. Amounts are each award's total.

Other open grants in the same program

Under assistance listing 93.113, 93.121, 93.142, 93.143, 93.172, 93.173, 93.213, 93.233, 93.242, 93.273, 93.279, 93.286, 93.307, 93.310, 93.313, 93.350, 93.351, 93.361, 93.372, 93.393, 93.394, 93.395, 93.396, 93.399, 93.837, 93.838, 93.839, 93.840, 93.846, 93.847, 93.853, 93.855, 93.859, 93.865, 93.866, 93.867, 93.879, 93.989, 93.ECH, the federal program this grant is paid from.

More open grants from the National Institutes of Health

340 open grants from this agency accept small businesses, with $356.4 million in total program funding listed.

All open federal grants for small businesses