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Advancing Real-World Effectiveness Evidence for Rapid-Acting Psychotropic Interventional Drugs (RAPIDs) (UM1 Clinical Trial Required)

Updated

Cooperative agreement from the National Institutes of Health, open to small businesses. Closes Jun 10, 2027, 208 days left.

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Opportunity numberRFA-MH-27-150
AgencyNational Institutes of Health
Funding typeCooperative agreement
FieldHealth
Expected number of awards3
Total program funding$12.0 million
Cost sharing or matchingNot required
Assistance listing93.24R, 93.DA1
PostedNov 12, 2026
ClosesJun 10, 2027 (208 days left)
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Who can apply

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;

Description

This notice of funding opportunity (NOFO) encourages applications to establish a Rapid-Acting Psychotropic Interventional Drugs - Clinical Trials Network (RAPIDs-CTN). The overarching purpose is to generate actionable, real-world evidence to guide the safe and effective implementation of RAPIDs in routine clinical practice, answering urgent questions about how these treatments can be delivered sustainably outside tightly controlled experimental settings.

This NOFO utilizes a milestone-driven UM1 Cooperative Agreement mechanism structured into two operational stages: Stage 1 (Years 1–2) for network establishment and pilot studies, and Stage 2 (Years 3–5) focuses for full-scale execution of proposed pragmatic trials. This program is intended only for large-scale, coordinated network projects that could not be achieved using other, more standard grant mechanisms.

Full announcement and how to apply on Grants.gov

Health grants right now

There are 347 open federal grants in health that small businesses may apply for; 24 close within 30 days. The median award ceiling is $500,000. The agencies offering the most are National Institutes of Health, Centers for Disease Control and Prevention - ERA and Health Resources and Services Administration. Grants in this field stay open a median of 1035 days; this one is open for 210 days.

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