Animal and Biological Material Resource Centers (P40 Clinical Trial Not Allowed)

Updated Oct 20, 2026

Grant from the National Institutes of Health, open to small businesses. Closes Sep 26, 2028, 707 days left.

Opportunity number	RFA-OD-25-011
Agency	National Institutes of Health
Funding type	Grant
Field	Health
Expected number of awards	2
Total program funding	$1.3 million
Cost sharing or matching	Not required
Assistance listing	93.351
Posted	Dec 5, 2025
Closes	Sep 26, 2028 (707 days left)
Add the deadline to	Google Calendar

Who can apply

State governments
County governments
City or township governments
Special district governments
Public and state controlled institutions of higher education
Nonprofits with 501(c)(3) status, other than institutions of higher education
Nonprofits without 501(c)(3) status, other than institutions of higher education
Private institutions of higher education
For-profit organizations other than small businesses
Small businesses
Others (see the eligibility notes)

Refer to Section III. Eligibility Information for additional information on eligibility. Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Description

This Notice of Funding Opportunity (NOFO) encourages grant applications for Animal and Biological Material Resource Centers. These Centers provide support for special colonies of laboratory animals and associated services, as well as other resources such as informatics tools, reagents, cultures (cells, tissues, and organs) and genetic stocks that serve the biomedical research community in a variety of research areas on a local, regional, and national basis.

The goal of projects supported by this NOFO is to provide research resources that facilitate optimization and enhancement of scientific rigor, transparency, and experimental reproducibility of biomedical research. Proposed Animal and Biological Material Resource Centers must have broad application to multiple NIH Institutes or Centers (ICs) to align with the ORIP"s NIH-wide mission (orip.nih.gov/about-orip).

This funding opportunity is designed to support both continuation of existing resources and to develop new ones when appropriate. Of special interest of the announcement is a requirement of the Center"s close coordination with efforts to develop new approach methodologies (NAMs) that complement traditional animal-based research. These include cell culture, organoids, computational models, and microphysiological systems.

Applied Research Component should include studies to generate comparative data to increase applicability of NAMs and promote integration of the most predictive human disease models. Prior to preparing an application, all applicants are strongly encouraged to consult with Scientific/Research staff to be advised on appropriateness of the intended resource plans for this program, competitiveness of a potential application, and ORIP's program priorities.

Full announcement and how to apply on Grants.gov

Health grants right now

There are 350 open federal grants in health that small businesses may apply for; 33 close within 30 days. The median award ceiling is $500,000. The agencies offering the most are National Institutes of Health, Centers for Disease Control and Prevention - ERA and Centers for Disease Control - NCBDDD. Grants in this field stay open a median of 1031 days; this one is open for 1026 days.

Who has won this program before

Oregon Health & Science University $203.0 million · from May 1, 1997
University Of Washington $201.8 million · from Jun 10, 1997
University Of California, Davis $191.3 million · from May 1, 1997
Emory University $167.0 million · from May 1, 1997
University Of Wisconsin System $150.2 million · from Jun 10, 1997

The largest grants and cooperative agreements under assistance listing 93.351 with payments since Oct 1, 2025, from USAspending.gov. Amounts are each award's total.