Continuation of the Cardiovascular Repository for-Type 1 Diabetes (CARE-T1D) Consortium U01 (Open Competition)- Research (U01, Clinical Trial Not Allowed)
Updated
Cooperative agreement from the National Institutes of Health, open to small businesses. Closes Mar 10, 2027, 141 days left.
| Opportunity number | RFA-DK-27-108 |
|---|---|
| Agency | National Institutes of Health |
| Funding type | Cooperative agreement |
| Field | Health |
| Award ceiling | $500,000 |
| Expected number of awards | 8 |
| Total program funding | $6.0 million |
| Cost sharing or matching | Not required |
| Assistance listing | 93.233, 93.837, 93.838, 93.839, 93.840, 93.847 |
| Posted | Jun 4, 2026 |
| Closes | Mar 10, 2027 (141 days left) |
| Add the deadline to | Google Calendar |
Who can apply
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and state controlled institutions of higher education
- Native American tribal governments (federally recognized)
- Public housing authorities and Indian housing authorities
- Native American tribal organizations (other than federally recognized tribal governments)
- Nonprofits with 501(c)(3) status, other than institutions of higher education
- Nonprofits without 501(c)(3) status, other than institutions of higher education
- Private institutions of higher education
- For-profit organizations other than small businesses
- Small businesses
- Others (see the eligibility notes)
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Description
The NIH Cardiovascular Repository for Type 1 Diabetes (CaRe-T1D) was created to improve research on type 1 diabetes (T1D) and cardiovascular disease (CVD). Cardiovascular complications remain the top cause of death among people with T1D and greatly shorten lifespan. The mechanisms underlying atherosclerosis, cardiomyopathy, endothelial dysfunction, and cardiac autonomic neuropathy in T1D remain poorly understood.
While managing traditional risk factors—such as high blood glucose, high blood pressure, and elevated cholesterol lower cardiovascular risk, a significant residual risk remains even with optimal control. In addition to atherosclerosis, both diastolic and systolic diabetic cardiomyopathy play a major role in morbidity and mortality among these patients. Currently, no therapies are specifically approved to prevent or treat these common and severe cardiovascular issues in T1D. The purpose of this NOFO is to promote collaborative and interdisciplinary research aimed at enhancing the understanding of the development of CVD in individuals with T1D and the differences with CVD in T1D by continuing the efforts of the CaRe-T1D consortium.This NOFO is associated with the Special Diabetes Program (niddk.nih.gov/about-niddk/resea...) which funds research on the prevention, treatment, and cure of type 1 diabetes and its complications, including unique, innovative, and collaborative research consortia and clinical trials networks.
Full announcement and how to apply on Grants.gov
Health grants right now
There are 350 open federal grants in health that small businesses may apply for; 33 close within 30 days. The median award ceiling is $500,000; this grant offers up to $500,000. The agencies offering the most are National Institutes of Health, Centers for Disease Control and Prevention - ERA and Centers for Disease Control - NCBDDD. Grants in this field stay open a median of 1031 days; this one is open for 279 days.
Who has won this program before
- Beth Israel Deaconess Medical Center, Inc. $19.3 million · from Jul 1, 2020
- Brigham & Womens Hospital Inc $15.0 million · from Aug 1, 1998
- Trustees Of The University Of Pennsylvania, The $7.4 million · from Sep 1, 2000
- Northwestern University $7.2 million · from Jul 1, 1998
- George Washington University (The) $7.1 million · from Jun 15, 2016
The largest grants and cooperative agreements under assistance listing 93.233, 93.837, 93.838, 93.839, 93.840, 93.847 with funding activity since Oct 1, 2025, from USAspending.gov. Amounts are each award's total.
Other open grants in the same program
Under assistance listing 93.233, 93.837, 93.838, 93.839, 93.840, 93.847, the federal program this grant is paid from.
More open grants from the National Institutes of Health
340 open grants from this agency accept small businesses, with $356.4 million in total program funding listed.