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Exploratory/Developmental Grants Related to the World Trade Center Health Program (R21)

Updated

Grant from the Centers for Disease Control and Prevention - ERA, open to small businesses. Closes Dec 8, 2026, 49 days left.

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Opportunity numberRFA-OH-26-015
AgencyCenters for Disease Control and Prevention - ERA
Funding typeGrant
FieldHealth
Award ceiling$365,000
Expected number of awards36
Total program funding$18.0 million
Cost sharing or matchingNot required
Assistance listing93.262
PostedMay 8, 2026
ClosesDec 8, 2026 (49 days left)
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Who can apply

Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the HHS Grants Policy Statement, are not allowed.

Description

The World Trade Center (WTC) Health Program supports exploratory and developmental research projects (R21) that address issues related to diagnostic or treatment uncertainty among individuals receiving monitoring and/or treatment under Subtitle C of the James Zadroga 9/11 Health and Compensation Act of 2010, as amended. This R21 Notice of Funding Opportunity (NOFO) is intended to encourage exploratory/developmental research by supporting the early and conceptual stages of project development to assess the feasibility of new areas of investigation with the potential to improve treatment effectiveness and diagnostic practices.

These studies may lead to breakthroughs in a particular area or to the development of new interventions, techniques, agents, methodologies, models, or approaches with potential clinical impact. They are expected to break new ground or extend prior discoveries in new directions or applications. Applicants are expected to propose research for which there is likely to be minimal or no preliminary data.

Full announcement and how to apply on Grants.gov

Health grants right now

There are 350 open federal grants in health that small businesses may apply for; 33 close within 30 days. The median award ceiling is $500,000; this grant offers up to $365,000. The agencies offering the most are National Institutes of Health, Centers for Disease Control and Prevention - ERA and Centers for Disease Control - NCBDDD. Grants in this field stay open a median of 1031 days; this one is open for 214 days.

Who has won this program before

The largest grants and cooperative agreements under assistance listing 93.262 with payments since Oct 1, 2025, from USAspending.gov. Amounts are each award's total.

Other open grants in the same program

Under assistance listing 93.262, the federal program this grant is paid from.

National Center for Construction Safety and Health Research and Translation (U54)
Centers for Disease Control and Prevention - ERA
Closes Dec 1, 2026 · 42 days left
Cooperative agreement · Up to $5.8 million an award · RFA-OH-24-001
Cooperative Research Agreements Related to the World Trade Center Health Program (U01)
Centers for Disease Control and Prevention - ERA
Closes Dec 8, 2026 · 49 days left
Cooperative agreement · Up to $550,000 an award · Open to any applicant · RFA-OH-26-001
Commercial Fishing Occupational Safety Research Cooperative Agreement (U01)
Centers for Disease Control and Prevention - ERA
Closes Jan 31, 2028
Cooperative agreement · Up to $975,000 an award · RFA-OH-22-005
Commercial Fishing Occupational Safety Training Project Grants (T03)
Centers for Disease Control and Prevention - ERA
Closes Jan 31, 2028
Grant · Up to $975,000 an award · RFA-OH-22-006
Occupational Safety and Health Education and Research Centers (T42)
Centers for Disease Control and Prevention - ERA
Closes Oct 26, 2028
Grant · Up to $9.0 million an award · Open to any applicant · RFA-OH-25-002

More open grants from the Centers for Disease Control and Prevention - ERA

7 open grants from this agency accept small businesses, with $158.2 million in total program funding listed.

Occupational Safety and Health Training Project Grants (T03)
Centers for Disease Control and Prevention - ERA
Closes Oct 26, 2028
Grant · Up to $550,000 an award · Open to any applicant · RFA-OH-25-003

All open federal grants for small businesses