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NextTech: Translational Development of Next-Generation Diagnostic and Therapeutic Devices (R18 Clinical Trial Not Allowed)

Updated

Grant from the National Institutes of Health, open to small businesses. Closes Dec 1, 2030, 1498 days left.

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Opportunity numberRFA-EB-28-004
AgencyNational Institutes of Health
Funding typeGrant
FieldHealth
Expected number of awards4
Total program funding$6.0 million
Cost sharing or matchingNot required
Assistance listing93.121, 93.242, 93.273, 93.279, 93.286, 93.853, 93.865, 93.866, 93.867
PostedOct 23, 2026
ClosesDec 1, 2030 (1498 days left)
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Who can apply

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Description

This Notice of Funding Opportunity (NOFO) is to encourage applications from investigators to advance the development and translation of next-generation technologies to prevent, monitor, diagnose, and treat disorders within the missions of the NIH Brain Research through Advancing Innovative Neurotechnologies (BRAIN) and The Helping to End Addiction Long-term (HEAL) Initiatives. Awarded activities will facilitate the translation of new devices up to the stage of readiness for first in human (FIH) clinical trials by overcoming key challenges identified during preliminary proof-of-concept studies.

The scope of the program includes technology development and optimization, and studies to prepare for approvals for human use.

Full announcement and how to apply on Grants.gov

Health grants right now

There are 354 open federal grants in health that small businesses may apply for; 35 close within 30 days. The median award ceiling is $500,000. The agencies offering the most are National Institutes of Health, Centers for Disease Control and Prevention - ERA and Centers for Disease Control - NCBDDD. Grants in this field stay open a median of 1030 days; this one is open for 1500 days.

Who has won this program before

The largest grants and cooperative agreements under assistance listing 93.121, 93.242, 93.273, 93.279, 93.286, 93.853, 93.865, 93.866, 93.867 with funding activity since Oct 1, 2025, from USAspending.gov. Amounts are each award's total.

Other open grants in the same program

Under assistance listing 93.121, 93.242, 93.273, 93.279, 93.286, 93.853, 93.865, 93.866, 93.867, the federal program this grant is paid from.

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