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Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional)

Updated

Cooperative agreement from the National Institutes of Health, open to small businesses. Closes Mar 6, 2027, 137 days left.

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Opportunity numberPAR-26-116
AgencyNational Institutes of Health
Funding typeCooperative agreement
FieldHealth
Award ceiling$500,000
Cost sharing or matchingNot required
Assistance listing93.313
PostedDec 8, 2025
ClosesMar 6, 2027 (137 days left)
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Who can apply

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility. Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. This new requirement was effective, May 1, 2025.Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.

Description

The goal of this program is to support collaborative translational research projects aligned with NIH efforts to enhance the translation of basic biological discoveries into clinical applications that improve health. It encourages high quality science demonstrating the potential to result in understanding an important disease process or lead to new therapeutic interventions, diagnostics, or prevention strategies within the research interests and priorities of the participating NIH Institutes/Centers (ICs).Specifically, the program seeks to broaden and strengthen translational research collaborations between basic and clinical researchers both within and outside NIH to accelerate and enhance translational science by promoting partnerships between NIH intramural investigators (e.g., those conducting research within the labs and clinics of the NIH) and extramural investigators (e.g., those conducting research in labs outside the NIH), and by providing support for extramural investigators to take advantage of the unique research opportunities available at the NIH Clinical Center by conducting clinical research projects in collaboration with NIH intramural investigators.

Full announcement and how to apply on Grants.gov

Health grants right now

There are 350 open federal grants in health that small businesses may apply for; 33 close within 30 days. The median award ceiling is $500,000; this grant offers up to $500,000. The agencies offering the most are National Institutes of Health, Centers for Disease Control and Prevention - ERA and Centers for Disease Control - NCBDDD. Grants in this field stay open a median of 1031 days; this one is open for 453 days.

Who has won this program before

The largest grants and cooperative agreements under assistance listing 93.313 with payments since Oct 1, 2025, from USAspending.gov. Amounts are each award's total.

Other open grants in the same program

Under assistance listing 93.313, the federal program this grant is paid from.

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Closes Nov 16, 2026 · 27 days left
Grant · Up to $50,000 an award · PAR-25-370
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National Institutes of Health
Closes Nov 18, 2026 · 29 days left
Grant · PAR-25-369
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)
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Closes Nov 18, 2026 · 29 days left
Grant · PAR-25-371
Maximizing the Scientific Value of Data Generated by the Environmental Influences on Child Health Outcomes (ECHO) Program: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (F32)
National Institutes of Health
Closes Dec 2, 2026 · 43 days left
Grant · RFA-OD-27-008
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)
National Institutes of Health
Closes Jan 7, 2027
Grant · PAR-25-379

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340 open grants from this agency accept small businesses, with $356.4 million in total program funding listed.

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All open federal grants for small businesses