SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Optional)
Updated
Grant from the National Institutes of Health, open to small businesses. Closes Apr 5, 2029, 898 days left.
| Opportunity number | PAR-27-098 |
|---|---|
| Agency | National Institutes of Health |
| Funding type | Grant |
| Field | Health |
| Cost sharing or matching | Not required |
| Assistance listing | 93.113, 93.121, 93.143, 93.172, 93.173, 93.233, 93.242, 93.273, 93.286, 93.307, 93.313, 93.350, 93.351, 93.393, 93.394, 93.395, 93.837, 93.838, 93.839, 93.840, 93.846, 93.847, 93.853, 93.855, 93.859, 93.865, 93.866, 93.867 |
| Posted | May 28, 2026 |
| Closes | Apr 5, 2029 (898 days left) |
| Add the deadline to | Google Calendar |
Who can apply
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and state controlled institutions of higher education
- Native American tribal governments (federally recognized)
- Public housing authorities and Indian housing authorities
- Native American tribal organizations (other than federally recognized tribal governments)
- Nonprofits with 501(c)(3) status, other than institutions of higher education
- Nonprofits without 501(c)(3) status, other than institutions of higher education
- Private institutions of higher education
- For-profit organizations other than small businesses
- Small businesses
- Others (see the eligibility notes)
Only United States small business concerns (SBCs), as defined by the Small Business Administration (SBA)(sbir.gov/apply) are eligible to submit applications for this opportunity.Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Unfunded international collaborations or unfunded foreign components, as defined in the NIH Grants Policy Statement, may be allowed.
Description
The Commercialization Readiness Pilot (CRP) program helps small business concerns (SBCs) move NIH-funded SBIR or STTR projects from late-stage development to commercialization. The CRP supports later-stage research and development (R&D) and/or technical assistance that Phase II and Phase IIB Strategic Breakthrough awards do not typically support. This includes:Independent replication or confirmation of key studiesIND- or IDE-enabling studiesClinical studiesManufacturing scale-up and related quality activitiesRegulatory and other specialized technical supportSBCs may subcontract (outsource) a significant amount of the work in a CRP to meet the project goals.
Full announcement and how to apply on Grants.gov
Health grants right now
There are 350 open federal grants in health that small businesses may apply for; 33 close within 30 days. The median award ceiling is $500,000. The agencies offering the most are National Institutes of Health, Centers for Disease Control and Prevention - ERA and Centers for Disease Control - NCBDDD. Grants in this field stay open a median of 1031 days; this one is open for 1043 days.
Who has won this program before
- Duke University $200.6 million · from Sep 21, 2016
- University Of North Carolina AT Chapel Hill $49.7 million · from Jul 1, 2007
- The General Hospital Corporation $49.2 million · from Jul 1, 2012
- Baylor College Of Medicine $47.8 million · from Sep 28, 2011
- Jackson Laboratory $47.2 million · from Sep 16, 2011
The largest grants and cooperative agreements under assistance listing 93.113, 93.121, 93.143, 93.172, 93.173, 93.233, 93.242, 93.273, 93.286, 93.307, 93.313, 93.350, 93.351, 93.393, 93.394, 93.395, 93.837, 93.838, 93.839, 93.840, 93.846, 93.847, 93.853, 93.855, 93.859, 93.865, 93.866, 93.867 with payments since Oct 1, 2025, from USAspending.gov. Amounts are each award's total.
Other open grants in the same program
Under assistance listing 93.113, 93.121, 93.143, 93.172, 93.173, 93.233, 93.242, 93.273, 93.286, 93.307, 93.313, 93.350, 93.351, 93.393, 93.394, 93.395, 93.837, 93.838, 93.839, 93.840, 93.846, 93.847, 93.853, 93.855, 93.859, 93.865, 93.866, 93.867, the federal program this grant is paid from.
More open grants from the National Institutes of Health
340 open grants from this agency accept small businesses, with $356.4 million in total program funding listed.