Seed Instrumentation Support (SIS) Program (S10 Clinical Trial Not Allowed)
Updated
Grant from the National Institutes of Health, open to small businesses. Closes Jul 1, 2028, 620 days left.
| Opportunity number | PAR-27-021 |
|---|---|
| Agency | National Institutes of Health |
| Funding type | Grant |
| Field | Health |
| Award ceiling | $400,000 |
| Award floor | $50,000 |
| Cost sharing or matching | Not required |
| Assistance listing | 93.310, 93.351, 93.855, 93.866 |
| Posted | Jun 25, 2026 |
| Closes | Jul 1, 2028 (620 days left) |
| Add the deadline to | Google Calendar |
Who can apply
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and state controlled institutions of higher education
- Native American tribal governments (federally recognized)
- Public housing authorities and Indian housing authorities
- Native American tribal organizations (other than federally recognized tribal governments)
- Nonprofits with 501(c)(3) status, other than institutions of higher education
- Nonprofits without 501(c)(3) status, other than institutions of higher education
- Private institutions of higher education
- For-profit organizations other than small businesses
- Small businesses
- Others (see the eligibility notes)
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Description
This Notice of Funding Opportunity (NOFO) aims to build new research capacity and develop a sustainable research program by supporting the purchase of a single commercially available biomedical research instrument currently unavailable in the institution. Instruments funded through this program must be shared among the users to create new research opportunities, enable reproducible data generation, encourage collaborative research and training, and strengthen long-term research capabilities.
The minimum award is $50,000. While there is no limit on the total cost of the instrument, the maximum award is $400,000.
Full announcement and how to apply on Grants.gov
Health grants right now
There are 350 open federal grants in health that small businesses may apply for; 33 close within 30 days. The median award ceiling is $500,000; this grant offers up to $400,000. The agencies offering the most are National Institutes of Health, Centers for Disease Control and Prevention - ERA and Centers for Disease Control - NCBDDD. Grants in this field stay open a median of 1031 days; this one is open for 737 days.
Who has won this program before
- University Of North Carolina AT Chapel Hill $977.0 million · from Jun 29, 2006
- Fred Hutchinson Cancer Center $383.5 million · from Jun 29, 2006
- Icahn School Of Medicine AT Mount Sinai $250.0 million · from Mar 1, 2006
- Dana-Farber Cancer Institute, Inc. $235.8 million · from Dec 1, 1977
- Oregon Health & Science University $203.0 million · from May 1, 1997
The largest grants and cooperative agreements under assistance listing 93.310, 93.351, 93.855, 93.866 with funding activity since Oct 1, 2025, from USAspending.gov. Amounts are each award's total.
Other open grants in the same program
Under assistance listing 93.310, 93.351, 93.855, 93.866, the federal program this grant is paid from.
More open grants from the National Institutes of Health
340 open grants from this agency accept small businesses, with $356.4 million in total program funding listed.