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Amendment 4 10 June

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A PDF document (275 KB) attached to Proactive Health Office (PHO) Mission Office Innovative Solutions Opening (ISO), from the National Institutes of Health. Due Mar 5, 2029, 11:59 PM (UTC-5).

File name: SOL-24-106_AMEND 04_10 June.pdf

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ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH

PROACTIVE HEALTH OFFICE

MISSION OFFICE INNOVATIVE SOLUTIONS OPENING (ISO)

ARPA-H-SOL-24-106

Amendment 04: June 10, 2026

ARPA-H-SOL-24-106

Amendment 04

1.0

2.0

2.1
2.2
2.3
2.4
3.0

3.1
3.2
PROHIBITION OF PERFORMER PARTICIPATION FROM FEDERALLY FUNDED R ESEARCH AND DEVELOPMENT 3.3
3.4
4.0
4.1
4.2
4.3
4.4
4.5
4.6
5.0
5.1
5.2
1.
2.
3.
4.
5.3
5.4
5.5
6.0

6.1

i

ARPA-H-SOL-24-106

Amendment 04

ATTACHMENT 1: BUNDLE OF ATTACHMENTS (OTHER TRANSACTION)

ii

ARPA-H-SOL-24-106

AMENDMENT 04

1.0

Innovative Solutions Opening Solicitation Overview Information

FEDERAL AGENCY NAME:

SOLICITATION TITLE:

SOLICITATION NUMBER:

Advanced Research Projects Agency for Health

(ARPA-H)

ARPA-H Proactive Health Office
Mission Office Innovative Solutions Opening (ISO)

ARPA-H-SOL-24-106

SOLUTION SUMMARY AND PROPOSAL

SUBMISSIONS

(ARPA-H SOLUTIONS SITE):

ISO QUESTIONS

(ARPA-H SOLUTIONS SITE):

DATES/TIMES:

RELEASE AND AMENDMENT DATES:

QUESTIONS & ANSWERS (Q&A) DUE DATE:

https://solutions.arpa-h.gov/Submit-Solution/
https://solutions.arpa-h.gov/Ask-A-Question/
All times listed herein are Eastern Time
Release:
March 14, 2024
Amendment 01:
September 25, 2024
Amendment 02:
June 06, 2025
Amendment 03:
October 14, 2025
Amendment 04:
June 10, 2026
Questions may be asked while this solicitation is
open

CLOSING DATE:

The solicitation will remain open until March 5, 2029

ANTICIPATED AWARD:

Multiple awards are anticipated

TYPES OF INSTRUMENTS THAT MAY BE

AWARDED:

Other Transactions (OTs)

PROPOSERS/ELIGIBLE ENTITIES:

Academia, Non-Profit Organizations, and For-Profit
Entities

RESOURCE SHARING:

Resource sharing may be encouraged or requested

ARPA-H-SOL-24-106

AMENDMENT 04

2.0

DESCRIPTION OF THE SOLICITATION:

2.1

INTRODUCTION

Despite advances in the development of novel medical the

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