Statement of Work Bayesian Software post mod 0001

Statement of Work (SOW)
Electronic Drug Reference Subscription
Introduction and Overview

This statement of work is for a subscription to a Bayesian-guided medication dosing software from a contractor that can provide licensing rights. This subscription is to ensure clinicians have access to a reliable web-based therapeutic drug dosing and monitoring tool for complex clinical situations that require careful drug therapy evaluation and adjustment in a systematic and efficient manner. The software will include important pharmacokinetic parameters and empiric and patient-specific dosing recommendations; allow for graphical prediction and projection of theoretical doses at any drug dosing interval in order to optimize and achieve therapeutic drug levels; provide local storage of data and references for primary literature of clinicals models used; and lastly, be highly customizable, HIPAA and GDPR compliant, and meet VA information security requirements by only providing patient de-identification information on the web-based platform. Must be fully compliant with the IDSA/ASHP Vancomycin 2020 guidelines.

Background

Intravenous vancomycin remains an important first-line antibiotic used for treatment of serious methicillin-resistant Staphylococcus aureus (MRSA) infections. Recent Consensus Guidelines (Rybak MJ et al, AM J HEALTH-SYST PHARM, March 2020) for vancomycin therapeutic monitoring now recommend vancomycin dose optimization preferably using a Bayesian-guided software to achieve individualized targeted concentrations that maximize clinical efficacy while minimizing renal toxicity. Veterans Affairs Healthcare Systems are complex in scope of services; thus, clinical providers require access to a validated, systematic, and intuitive clinical tool to dose and monitor drug therapy safely.

Scope of Work

Business Area Agreement is not required.
The contractor shall provide uninterrupted licensing and subscription services to a Bayesian-guided medication dosing software as stated herein for clinical staff within the VA Salt Lake City Health Care System.

Performance Period
Contract will start December 12/1/2026 to 11/30/2027 with four 12-month renewal options. Period(s) of Performance:
12/1/2026 to 11/30/2027 Base Year
12/1/2027 to 11/30/2028 Option Year 1
12/1/2028 to 11/30/2029 Option Year 2
12/1/2029 to 11/30/2030 Option Year 3
12/1/2030 to 11/30/2031 Option Year 4

Requirements

License rights to a web-based pharmacokinetics medication dosing software program from a contractor that can provide license rights equivalent to or exceeding the product listing offered by the proprietor.