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FY 2027 Continuation of Solicitation for the Office of Science Financial Assistance Program

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Cooperative agreement or Grant or Other or Procurement contract from the Office of Science, open to any type of applicant. Closes Sep 30, 2027, 345 days left.

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Opportunity numberDE-FOA-0003665
AgencyOffice of Science
Funding typeCooperative agreement or Grant or Other or Procurement contract
FieldScience, technology and other research and development
Award ceiling$10.0 million
Award floor$5,000
Total program funding$400.0 million
Cost sharing or matchingNot required
Assistance listing81.049
PostedSep 30, 2026
ClosesSep 30, 2027 (345 days left)
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Who can apply

Description

SC hereby announces its continuing interest in receiving applications for support of work in the following program areas: · Advanced Scientific Computing Research· Basic Energy Sciences· Biological and Environmental Research· Fusion Energy Sciences· High Energy and Nuclear Physics· Isotope R&D and Production. On September 3, 1992, DOE published in the Federal Register the Office of Energy Research Financial Assistance Program (now called the Office of Science Financial Assistance Program), 10 C.F.R. part 605, as a Final Rule, which contained a solicitation for this program.

Information about submitting applications, eligibility, limitations, evaluation and selection processes and other policies and procedures are specified in 10 C.F.R. part 605.This NOFO is our annual open solicitation that covers all research areas in SC and is open throughout the fiscal year (FY). Any research within SC’s congressionally authorized mission may be proposed under this NOFO.This NOFO will remain open until September 30, 2027, 11:59 PM Eastern Time, or until it is succeeded by another issuance, whichever occurs first.

Full announcement and how to apply on Grants.gov

Science, technology and other research and development grants right now

There are 99 open federal grants in science, technology and other research and development that small businesses may apply for; 46 close within 30 days. The median award ceiling is $1.2 million; this grant offers up to $10.0 million. The agencies offering the most are Defense Health Agency Contracting Activity - DHACA, U.S. National Science Foundation and National Institute of Justice. Grants in this field stay open a median of 154 days; this one is open for 365 days.

Who has won this program before

The largest grants and cooperative agreements under assistance listing 81.049 with payments since Oct 1, 2025, from USAspending.gov. Amounts are each award's total.

Other open grants in the same program

Under assistance listing 81.049, the federal program this grant is paid from.

The Genesis Mission: Transforming Science and Energy with AI
Office of Science
Closes Dec 17, 2026 · 58 days left
Other · Up to $16.0 million an award · Open to any applicant · DE-FOA-0003612

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