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Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Assay Development and Neurotherapeutic Agent Identification (R61/R33 Clinical Trial Not Allowed)

Updated

Grant from the National Institutes of Health, open to small businesses. Closes Oct 20, 2027, 365 days left.

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Opportunity numberPAR-25-059
AgencyNational Institutes of Health
Funding typeGrant
FieldHealth
Award ceiling$750,000
Total program funding$750,000
Cost sharing or matchingNot required
Assistance listing93.853
PostedOct 22, 2024
ClosesOct 20, 2027 (365 days left)
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Who can apply

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Description

This funding opportunity announcement (FOA) encourages research grant applications to develop in vitro and/or ex vivo assays and conduct iterative screening efforts to identify and characterize potential therapeutic agents for neurological or neuromuscular disorders. This FOA is part of a suite of Innovation Grants to Nurture Initial Translational Efforts (IGNITE) to advance projects to the point where they can meet the entry criteria for the Blueprint Neurotherapeutics Network (BPN) or other translational programs.

Full announcement and how to apply on Grants.gov

Health grants right now

There are 350 open federal grants in health that small businesses may apply for; 33 close within 30 days. The median award ceiling is $500,000; this grant offers up to $750,000. The agencies offering the most are National Institutes of Health, Centers for Disease Control and Prevention - ERA and Centers for Disease Control - NCBDDD. Grants in this field stay open a median of 1031 days; this one is open for 1093 days.

Who has won this program before

The largest grants and cooperative agreements under assistance listing 93.853 with payments since Oct 1, 2025, from USAspending.gov. Amounts are each award's total.

Other open grants in the same program

Under assistance listing 93.853, the federal program this grant is paid from.

HEAL Initiative: Whole Joint Health Program (R61/R33 Clinical Trial Required)
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Closes Oct 30, 2026 · 10 days left
Grant · PAR-27-045
Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)
National Institutes of Health
Closes Nov 10, 2026 · 21 days left
Cooperative agreement · RFA-NS-26-001
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)
National Institutes of Health
Closes Nov 18, 2026 · 29 days left
Grant · PAR-25-369
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)
National Institutes of Health
Closes Nov 18, 2026 · 29 days left
Grant · PAR-25-371
NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional)
National Institutes of Health
Closes Nov 19, 2026 · 30 days left
Cooperative agreement · PAR-25-052

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All open federal grants for small businesses