Integrating Biospecimen Science Approaches into Clinical Assay Development (U01 Clinical Trial Not Allowed)
Updated
Cooperative agreement from the National Institutes of Health, open to small businesses. Closes Sep 10, 2027, 325 days left.
| Opportunity number | PAR-25-325 |
|---|---|
| Agency | National Institutes of Health |
| Funding type | Cooperative agreement |
| Field | Education, Health |
| Cost sharing or matching | Not required |
| Assistance listing | 93.393 |
| Posted | Dec 13, 2024 |
| Closes | Sep 10, 2027 (325 days left) |
| Add the deadline to | Google Calendar |
Who can apply
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and state controlled institutions of higher education
- Native American tribal governments (federally recognized)
- Public housing authorities and Indian housing authorities
- Native American tribal organizations (other than federally recognized tribal governments)
- Nonprofits with 501(c)(3) status, other than institutions of higher education
- Nonprofits without 501(c)(3) status, other than institutions of higher education
- Private institutions of higher education
- For-profit organizations other than small businesses
- Small businesses
- Others (see the eligibility notes)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Description
Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to support extramural research to investigate and mitigate challenges facing clinical assay development and subsequent analytical validation due to preanalytical variability in tumor tissue biopsies, blood biospecimens utilized as liquid biopsies", or other biospecimens as described in this NOFO.
Extramural research funded under this NOFO may include investigations of preanalytical variability associated with the procurement and study of small biopsies (core biopsies, small excision samples), blood utilized for "liquid biopsies", tissue swabs, tissue secretions, pleural and esophageal aspirates, feces, or bodily fluids like sweat, urine, CSF, breast milk and saliva. Investigator-designed experiments will explore how different biospecimen preanalytical conditions affect emerging and clinically relevant biomarkers quantified by a variety of testing platforms.
The results from this research program will improve the understanding of how analytical quantification of clinically relevant biomarkers is affected by variation in biospecimen collection, processing, and storage procedures. The overall goal is to expedite biomarker clinical assay development through evidence-based standardization of biopsy handling practices.
Full announcement and how to apply on Grants.gov
Education grants right now
There are 109 open federal grants in education that small businesses may apply for; 7 close within 30 days. The median award ceiling is $424,500. The agencies offering the most are National Institutes of Health and DOC NOAA - ERA Production. Grants in this field stay open a median of 1064 days; this one is open for 1001 days.
Who has won this program before
- Ecog-Acrin Medical Research Foundation, Inc. $199.7 million · from Aug 1, 2014
- American College Of Radiology $115.5 million · from May 26, 2014
- The Regents Of The University Of Colorado $82.6 million · from Apr 4, 1997
- Albert Einstein College Of Medicine $75.9 million · from Jun 1, 1997
- The Regents Of The University Of California $60.2 million · from Sep 27, 2001
The largest grants and cooperative agreements under assistance listing 93.393 with funding activity since Oct 1, 2025, from USAspending.gov. Amounts are each award's total.
Other open grants in the same program
Under assistance listing 93.393, the federal program this grant is paid from.
More open grants from the National Institutes of Health
340 open grants from this agency accept small businesses, with $356.4 million in total program funding listed.