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NIAID Investigator Initiated Program Project Applications (P01 Clinical Trial Not Allowed)

Updated

Grant from the National Institutes of Health, open to small businesses. Closes May 25, 2029, 948 days left.

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Opportunity numberPAR-27-082
AgencyNational Institutes of Health
Funding typeGrant
FieldHealth
Cost sharing or matchingNot required
Assistance listing93.855
PostedMay 7, 2026
ClosesMay 25, 2029 (948 days left)
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Who can apply

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Description

This notice of funding opportunity (NOFO) invites submission of investigator-initiated Program Project (P01) applications. The proposed Programs should address scientific areas relevant to the NIAID mission including: biology and pathogenesis of infectious microbes, including HIV; host-microbe interactions; mechanisms regulating immune system development and function across the lifespan, and in response to infectious pathogens; immune dysfunction resulting in allergy, asthma, autoimmunity, immunodeficiency, or transplant rejection; and translational research to develop vaccines, therapeutics, and diagnostics to prevent and treat infectious and immune-mediated diseases.

Each application submitted to this NOFO must include at least two related, synergistic Research Projects that share a common central theme, focus, and/or overall objective; and an Administrative Core. An application may include Scientific Core(s), if needed for the proposed research.

Full announcement and how to apply on Grants.gov

Health grants right now

There are 350 open federal grants in health that small businesses may apply for; 33 close within 30 days. The median award ceiling is $500,000. The agencies offering the most are National Institutes of Health, Centers for Disease Control and Prevention - ERA and Centers for Disease Control - NCBDDD. Grants in this field stay open a median of 1031 days; this one is open for 1114 days.

Who has won this program before

The largest grants and cooperative agreements under assistance listing 93.855 with payments since Oct 1, 2025, from USAspending.gov. Amounts are each award's total.

Other open grants in the same program

Under assistance listing 93.855, the federal program this grant is paid from.

Clinical Research Network on Antimicrobial Resistance (UM1 Clinical Trial Required)
National Institutes of Health
Closes Nov 10, 2026 · 21 days left
Cooperative agreement · RFA-AI-27-005
Infectious Diseases Clinical Trials Network (IDCTN) (UM1 Clinical Trial Required)
National Institutes of Health
Closes Nov 10, 2026 · 21 days left
Cooperative agreement · RFA-AI-27-002
Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)
National Institutes of Health
Closes Nov 16, 2026 · 27 days left
Grant · Up to $50,000 an award · PAR-25-370
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)
National Institutes of Health
Closes Nov 18, 2026 · 29 days left
Grant · PAR-25-369
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)
National Institutes of Health
Closes Nov 18, 2026 · 29 days left
Grant · PAR-25-371

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340 open grants from this agency accept small businesses, with $356.4 million in total program funding listed.

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All open federal grants for small businesses