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Protein Palace

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Solicitation from the Defense Advanced Research Projects Agency (DARPA). Due Jan 22, 2027, 70 days left.

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Solicitation numberDARPA-PA-27-02
AgencyDefense Advanced Research Projects Agency (DARPA)
OfficeDef Advanced Research Projects Agcy
Notice typeSolicitation
Set-asideNone
Trade (NAICS)Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) (541715)
Product or service codeAC12
PostedNov 12, 2026
Response deadlineJan 22, 2027 (70 days left)
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Bid documents (13)

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Description

The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative proposals in the area of tunable purification of any protein from complex feedstocks. Proposed research should investigate innovative approaches that enable revolutionary advances in science, devices, or systems. Specifically excluded is research that primarily results in evolutionary improvements to the existing state of practice.

Contracting contact

As published on the official notice. Ask questions in writing and before any questions deadline the notice sets.

Is your business small enough?

For NAICS 541715, a business counts as small if it has no more than 11 employees (SBA size standard, with exceptions in the notes). This notice is not set aside, but the size decides your small business status on it. SBA table, current as of Oct 15, 2026.

Companies that win this kind of work

Federal contractors paid for research and development in the physical, engineering, and life sciences work, who also hold DARPA contracts (last 12 months): possible competitors, or partners to team with.

About the buyer

The Defense Advanced Research Projects Agency awarded $1.3 billion in contracts in the last 12 months; its biggest suppliers were Lockheed Martin Corporation, The Johns Hopkins University Applied Physics Laboratory LLC and Securigence LLC. See what DARPA is buying now.

Research and Development in the Physical, Engineering, and Life Sciences contracts right now

There are 278 open government contract opportunities in this trade (NAICS 541715), 42 posted in the last 7 days; 29% are set aside for small businesses. The agencies buying the most are Department of the Air Force, Department of the Army and Defense Advanced Research Projects Agency (DARPA). Most of the work with a stated place is in Maryland, District of Columbia and Virginia. A notice in this trade gives a median of 47 days from posting to deadline; this one gives 71 days.

All open research and development in the physical, engineering, and life sciences contracts

Coming up in this trade

Planned contracts from the agencies' procurement forecasts, often months before a solicitation. Plans can change.

Replicable, Actionable Projects for Intelligent Transportation Systems (ITS) Deployment, Broad Agency Announcement (RAPID BAA)
Federal Highway Administration
$250M - $499M · Unrestricted · Combination
Detect Soil Drainage Using Electrical Resistivity Imaging Technique
Federal Railroad Administration
$500K - $999K · To Be Determined
Wayside Detector Technology Best Practices Phase 4
Federal Railroad Administration
$500K - $999K · To Be Determined

Recent awards in this trade

From the award notices agencies publish.

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